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Melha Mellata

Melha Mellata

  • Associate Professor
  • Interdepartmental Microbiology Graduate Program DOGE, 2022-2024
  • Food Science and Human Nutrition

Contact Info

3346 Food Sciences
536 Farm House Ln.
Social Media and Websites


  • PhD, University of Montreal
  • Post doc, Washington University
  • Post doc, Biodesign Institute, Arizona State University

More Information


MICRO 517: Gut Microbiota: Implications in Health & Diseases (3 Credits-Fall)

Recent Publications

  1. Redweik GAJ., MK Horak, R. Hoven, LC. Ott, and M Mellata. 2021 Evaluation of Live Bacterial Prophylactics to Decrease IncF Plasmid Transfer and Association With Intestinal Small RNAs. Front. Micro 11, 3581.
  2. Jochum JM, GAJ. Redweik, LC. Ott, and M Mellata. 2021. Bacteria Broadly-Resistant to Last Resort Antibiotics Detected in Commercial Chicken Farms. Microorganism 9 (1), 141.
  3.  Ott L., H. Appleton. S. Hu, K. Keener, and M Mellata. 2021 High-Voltage-Atmospheric Cold Plasma Inactivation of Fungal Spores and Deoxynivalenol Toxin In Vitro. Food Microbiol. doi: 10.1016/ Epub 2020 Nov 5
  4. Stromberg ZR, RE. Masonbrink, and M Mellata 2020 Transcriptomic Analysis of Shiga Toxin-Producing Escherichia coli during Initial Contact with Cattle Colonic Explants. Microorganisms
  5. Redweik GAJ., MH. Kogut, RJ. Arsenault, and M. Mellata2020 Oral Treatment with Ileal Spores Triggers Immunometabolic Shifts in Chicken Gut. Front. Vet. Sci., 08 September 2020 
  6. Redweik GAJ., J. Jochum, and M. Mellata2020 Live Bacterial Prophylactics in Modern Poultry. Front. Vet. Sci.
  7. Van Goor A., GAJ. Redweik, ZR. Stromberg, CG. Treadwell, H. Xin and M. Mellata2020 Microbiome and biological blood marker changes in hens at different laying stages in conventional and cage-free housings. Poult Sci. 99(5):2362-2374. doi: 10.1016/j.psj.2020.01.011. Epub 2020 Mar 19.
  8. Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata 2020 Protection against avian pathogenic Escherichia coli and Salmonella Kentucky exhibited in chickens given both probiotics and live Salmonella vaccine. Poult Sci.  99(2):752-762 doi: 10.1016/j.psj.2019.10.038. Epub 2019
  9. Redweik GAJ, Daniels K, Severin AJ, Lyte, and M, Mellata2020 Oral Treatments with Probiotics and Live Salmonella Vaccine Induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens. Front. Micro. 10:3064. doi: 10.3389/fmicb.2019.03064. eCollection 2019
  10. Ott LC., ZR. Stromberg, GAJ. Redweik, MJ. Wannemuehler, and M. Mellata. 2020 Mouse genetic background affects antibiotic-resistant plasmid transfer in the gastrointestinal tract. mSphere 5(1). pii: e00847-19. doi: 10.1128/mSphere.00847-19.
  11. Stromberg ZR., A. Van Goor, GAJ. Redweik, MJ. Wymore Brand, MJ. Wannemuehler, and M. Mellata2018 Pathogenic and non-pathogenic Escherichia coli colonization and host inflammatory response in a defined microbiota mouse model. Dis. Mod. Mech. dmm.035063 doi: 10.1242/dmm.035063 P.
  12. Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata2018 Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains. Front. Vet. Sci. doi: 10.3389/fvets.2018.00198.
  13. Stromberg ZR, GAJ. Redweik, and M Mellata. 2018 Detection and Cell-Based Methods for Evaluating Non-O157 Shiga Toxin-Producing Escherichia coli from Cattle. Foodborne Pathog Dis 15(3):119-131. (Invited-published in a special edition: 15thanniversary of the journal).
  14. Maddux JT, ZR. Stromberg, R. Curtiss 3rd, M. Mellata. 2017 Evaluation of Recombinant Attenuated Salmonella Vaccine Strains for Broad Protection against Extraintestinal Pathogenic Escherichia coliFront Immuno 8:1280. doi: 10.3389/fimmu.2017.01280.
  15. Van Goor A., ZR. Stromberg, and M. Mellata2017 A Recombinant Multi-Antigen Vaccine with Broad Protection Potential against Avian Pathogenic Escherichia coli. Vaccine PlosOne, 12(8): e0183929.
  16. Stromberg ZR, JR. Johnson, JM. Fairbrother, A. Van Goor, R. Curtiss 3rd, and M. Mellata. 2017. Evaluation of Escherichia coli isolates from healthy chickens to determine their potential risk to poultry and human health. PlosOne 12(7): e0180599.
  17. Mellata M., JR. Johnson, and R. Curtiss. 2017 Escherichia coli Isolates from Commercial Chicken Meat and Eggs Cause Sepsis, Meningitis, and Urinary Tract Infection in Rodent Models of Human Infection. Zoonoses and public Health 2017; 00:1–11.
  18. Mellata M., NM. Mitchell, F. Schödel, R. Curtiss 3rd, GB. Pier. 2016. Novel vaccine antigen combinations elicit protective immune responses against Escherichia coli sepsis. Vaccine 34 (5): 656-662


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Patents Granted

  1. Curtiss, R. III, M. Mellata, B. Zekarias, Z. Shi, C. Branger, and K. Roland. Recombinant bacterium capable of eliciting an immune response against enteric pathogens. Salmonella vaccine against bacterial enteric pathogens. U.S. Patent No. 8,465,755B2 filled 10/06/08 (granted 06/18/13).
  2. Mellata M. Recombinant Bacterium Comprising a Toxin/Antitoxin System as a Vaccine Vector.” U.S. Provisional Application No. 61/417,046 and No 61/417,030, filed 11/24/2010, PCT/US2011/061896,     filed   11/24/2011                       (granted         12/01/2015).