Melha Mellata

Melha Mellata

Position
  • Associate Professor
  • Faculty Senate
Department
  • Food Science and Human Nutrition

Contact

Email
mmellata@iastate.edu
Phone
515-294-9220
3346 Food Sciences
536 Farm House Ln.
Ames
,
IA
50011-1054
Social Media and Websites

Education

  • PhD, University of Montreal
  • Post doc, Washington University & Biodesign Institute, Arizona state University (R. Curtiss III)

Affiliations

Teaching:

MICRO 517: Gut Microbiota: Implications in Health & Diseases (3 Credits-Fall)

Recent Publications

  1. Publications (Selected)
  2. Ott LC. and M. Mellata. 2024. Short-chain fatty acids inhibit bacterial plasmid transfer through conjugation in vitro and in ex vivo chicken tissue explants. Front. Micro. V 15  https://doi.org/10.3389/fmicb.2024.1414401.
  3. Meinen-Jochum J.**, LC. Ott**, M. Mellata@ 2023. Segmented filamentous bacteria-based treatment to elicit protection against Enterobacteriaceae in Layer chickens. V. 14 - 2023 | https://doi.org/10.3389/fmicb.2023.1231837
  4. Redweik GAJ**, MH Kogut, RJ. Arsenault, M. Lyte, M. Mellata@. 2021 Reserpine improves Enterobacteriaceae resistance in chicken intestine via neuro-immunometabolic signaling and MEK1/2 activation. Nature Com Biol. 4 (1), 1-11.
  5. Redweik GAJ., MK Horak, R. Hoven, LC. Ott, and M Mellata. 2021 Evaluation of Live Bacterial Prophylactics to Decrease IncF Plasmid Transfer and Association With Intestinal Small RNAs. Front. Micro 11, 3581.
  6. Jochum JM, GAJ. Redweik, LC. Ott, and M Mellata. 2021. Bacteria Broadly-Resistant to Last Resort Antibiotics Detected in Commercial Chicken Farms. Microorganism 9 (1), 141.
  7. Redweik GAJ., J. Jochum, and M. Mellata. 2020 Live Bacterial Prophylactics in Modern Poultry. Front. Vet. Sci.   https://doi.org/10.3389/fvets.2020.592312
  8. Redweik GAJ, Daniels K, Severin AJ, Lyte, and M, Mellata. 2020 Oral Treatments with Probiotics and Live Salmonella Vaccine Induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens. Front. Micro. 10:3064. doi: 10.3389/fmicb.2019.03064. eCollection 2019
  9. Ott LC., ZR. Stromberg, GAJ. Redweik, MJ. Wannemuehler, and M. Mellata. 2020 Mouse genetic background affects antibiotic-resistant plasmid transfer in the gastrointestinal tract. mSphere 5(1). pii: e00847-19. doi: 10.1128/mSphere.00847-19.

More details on publications

Patents Granted

  1. Curtiss, R. III, M. Mellata, B. Zekarias, Z. Shi, C. Branger, and K. Roland. Recombinant bacterium capable of eliciting an immune response against enteric pathogens. Salmonella vaccine against bacterial enteric pathogens. U.S. Patent No. 8,465,755B2 filled 10/06/08 (granted 06/18/13).  https://www.google.com/patents/US8465755
  2. Mellata M. Recombinant Bacterium Comprising a Toxin/Antitoxin System as a Vaccine Vector.” U.S. Provisional Application No. 61/417,046 and No 61/417,030, filed 11/24/2010, PCT/US2011/061896,     filed   11/24/2011  (granted 12/01/2015).  https://www.google.ch/patents/WO2012087483A1?cl=en